ABSTRACT
Funding Acknowledgements Type of funding sources: None. Back ground – COVID-19 is reported in India from March 2020. It is known to cause myocarditis , arrythmias and heart failure. COVID-19 infection has been proposed to be associated with myocardial infarction. PURPOSE –We intent to study outcomes of acute coronary syndrome associated with COVID-19 patients . METHODS – This is a single center case-control study done in an University hospital in south India , from May 2020 to October 2020 . Data of patients who came with acute coronary syndrome (ACS) with COVID- 19 were collected retrospectively from the hospital database. The clinical outcomes of the these patients were compared with the patients who were admitted in the hospital for ACS without COVID -19 in the same period. RESULITS – 508 patients were admitted between May 2020 to October 2020 with ACS and out of which 58 patients were positive for COVID-19 and 450 patients were COVID-19 negative. In COVID positive group, most of the patients were above 50 years with 17 % of them being female sex. 60 % were having diabetes and 44.8 % had hypertension . 55% of them had STEMI with the rest being NSTE- ACS . 43.1 % patients were thrombolysed . 25% patients underwent revascularization either with PCI / CABG . 10.3% died in the COVID - 19 positive group , at the same time there were only 2.2 % deaths in the control group . Most the patients were asymptomatic COVID-19 at presentation . Among the symptomatic COVID-19 patients the onset of myocardial infarction after COVID-19 ranged from 9 – 90 days . CONCLUSION – Acute coronary syndrome in COVID-19 patients can present as late as 3 months after index infection, and these patients had higher mortality compared with those who did not have COVID -19 .
ABSTRACT
Back ground-COVID-19 is reported in India from March 2020. It is known to cause myocarditis , arrythmias and heart failure. COVID-19 infection has been proposed to be associated with myocardial infarction. PURPOSE -We intent to study outcomes of acute coronary syndrome associated with COVID-19 patients . METHODS-This is a single center case-control study done in an University hospital in south India , from May 2020 to October 2020 . Data of patients who came with acute coronary syndrome (ACS) with COVID- 19 were collected retrospectively from the hospital database. The clinical outcomes of the these patients were compared with the patients who were admitted in the hospital for ACS without COVID -19 in the same period. RESULITS-508 patients were admitted between May 2020 to October 2020 with ACS and out of which 58 patients were positive for COVID-19 and 450 patients were COVID-19 negative. In COVID positive group, most of the patients were above 50 years with 17 % of them being female sex. 60 % were having diabetes and 44.8 % had hypertension . 55% of them had STEMI with the rest being NSTEACS . 43.1 % patients were thrombolysed . 25% patients underwent revascularization either with PCI / CABG . 10.3% died in the COVID-19 positive group , at the same time there were only 2.2 % deaths in the control group . Most the patients were asymptomatic COVID-19 at presentation . Among the symptomatic COVID-19 patients the onset of myocardial infarction after COVID-19 ranged from 9-90 days . CONCLUSION-Acute coronary syndrome in COVID-19 patients can present as late as 3 months after index infection, and these patients had higher mortality compared with those who did not have COVID -19.
ABSTRACT
Background: The COVID-19 pandemic has transformed the medical society in many ways. With significant drain on the resources and altered healthcare priorities, there is a greater need for redeployment of the resources from noncommunicable diseases to COVID-19-related healthcare services. To understand the impact of the COVID-19 pandemic on the management of acute coronary syndrome (ACS) in Tamil Nadu, a survey was administered across cardiologists in Tamil Nadu. Methods: A survey was done using an electronic questionnaire administered regarding the change of patterns of acute coronary syndromes during the COVID through Google Forms with responses collected in excel format. Results: Among 256 cardiologists contacted, 101 responded to the survey. Among cardiologists who responded, all were interventional cardiologists- with most of them performing primary percutaneous coronary intervention (PCI) (95%) regularly during pre-COVID times. Most of them have noticed a significant reduction in the number of patients with ACS seeking health care (94%) and another 61% of respondents felt that there was a reduction in the number of patients with acute coronary syndrome. There was a significant delay in ST-segment elevation myocardial infarction presentation to the hospital (88%) and significant reduction in the number of primary PCI (47%). Only 19% of respondents did primary PCI for COVID-positive patients. Conclusions: COVID pandemic has emerged as a big challenge to the global health care system. Optimal acute coronary care could not be delivered in a timely manner due to multiple social, patient, and physician-related factors. The emerging techniques in rapid diagnosis of COVID-19 and protective measures of COVID infection are expected to improve the situation. Trial Registration: Clinical Trials Registry - India (CTRI), CTRI/2020/09/027517, Registered September 1, 2020 http://CTRI. nic. In/Clinicaltrials/pmaindet2. php? trialid = 47025 and EncHid = and user Name =.